Acknowledgements
I thank Gil Jansky for his very professional production of the videos, Zhenxing Fu and Amy Clay for help with preparing the PowerPoints, my colleagues Peter D. Wagner and Frank L. Powell for some of the material, my assistant Keith Lander for transcriptions, and Jess Mandel of the Deans office for financial assistance. Finally many of our excellent medical students have contributed through discussions of the material over the years.
Corrections
As the listener will immediately recognize, these lectures were not read but delivered "on the fly". This makes them less formal. However there are a number of slips of the tongue. For example in the description of the central chemoreceptors, the term blood-gas barrier should really be blood-brain barrier. In the short section on turbulent flow, I should have said that the pressure is approximately equal to the square of the flow, not that flow is related to the square of the pressure. In the section on exercise, the systemic vascular resistance (not the systemic pressure) falls during dynamic exercise but rises during static exercise. The pulmonary function experiment done by the astronaut takes 31 minutes (as shown in the image) not an hour. There are probably other slips of the tongue but the meaning should be clear in the context of the lectures.
Credits for Images
These lectures have been gradually developed over a period of 40 years and they contain over 300 images. In some instances the origin of the images is unknown. Since this is a non-commercial project solely for educational purposes I hope nobody will be offended. Here are the credits where the origin is known.
Structure and Function of the Lung:
2, 8, 33, 35 - Hansen J.T. and Koeppen B.M. Netters Atlas of Human Physiology. Teterboro, NJ: Icon Learning Systems, 2002.
3, 6, 18, 26, 32, 34 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
4, 5 - Weibel E.R. Physiological Reviews 53:419-495, 1973.
9, 10, 11, 14 - Norman Staub
Blood Gas Transport:
2, 3, 4, 5, 9, 10, 14, 16, 19, 20 - modified from Peter D. Wagner
8, 12, 13, 15, 18, 21, 22, 23, 24 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
Acid-Base Balance:
3 Guyton A.C. and Hall J.E. Textbook of Medical Physiology, 9th ed. Philadelphia: W.B. Saunders Company, 1996.
4, 5, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 23 - modified from Peter D. Wagner
7, 24, 25 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
26 Wilson et al. Am. J. Physiol. 233: 135-140, 1977.
Diffusion:
3, 4, 7, 9, 10, 12, 13, 15, 20 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
5, 6, 18 - Weibel E.R. Physiological Reviews 53:419-495, 1973.
11 - modified from Peter D. Wagner
14 West J.B. Pulmonary Pathophysiology: The Essentials, 7th ed. Philadelphia: Lippincott Williams and Wilkins, 2007.
Pulmonary Blood Flow:
2, 3, 4, 6, 7, 9, 10, 14, 15, 16, 17, 18, 19, 20, 21, 23, 24, 25, 28 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
5, 11 - Weibel E.R. Physiological Reviews 53:419-495, 1973.
22 - West J.B. Pulmonary Pathophysiology: The Essentials, 7th ed. Philadelphia: Lippincott Williams and Wilkins, 2007.
Pulmonary Gas Exchange I:
2, 3, 4, 5, 10, 11, 12, 14, 15, 17, 18 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
13 - West J.B. Pulmonary Pathophysiology: The Essentials, 7th ed. Philadelphia: Lippincott Williams and Wilkins, 2007.
Pulmonary Gas Exchange II:
2, 3, 4, 5, 6, 7, 8, 11, 12, 13, 14, 17, 18, 20 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
19 - West J.B. Pulmonary Pathophysiology: The Essentials, 7th ed. Philadelphia: Lippincott Williams and Wilkins, 2007.
9, 10 - West J. B. Regional Differences in the Lung. New York: Academic Press, 1977.
19, 21 - West J.B. Pulmonary Pathophysiology: The Essentials, 7th ed. Philadelphia: Lippincott Williams and Wilkins, 2007.
Mechanics of Breathing I:
2, 3, 4, 5, 6, 7, 10, 11, 12, 13, 17, 18, 20, 21, 24, 25, 26 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
Mechanics of Breathing II:
2, 4, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16 - West J.B. Respiratory Physiology: The Essentials. Philadelphia:Lippincott Williams and Wilkins, 2008.
Control of Ventilation:
2, 6, 8, 11, 12 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
3 - Cancer Help UK
Respiration Under Stress:
4,7, 9, 15 - West J.B. Respiratory Physiology: The Essentials. Philadelphia: Lippincott Williams and Wilkins, 2008.
Respiration at the Limit:
26, 27, 28, 29, 30, 31 - West J.B. Pulmonary gas exchange on the summit of Mt. Everest. J. Appl. Physiol. 55: 678-687, 1983.
